On one Windows 2008 R2 Standard SP1 server we have observed an problem where pdfCreator will crash when called from the command line.
This problem is intermittant and as yet we have been unable to replicate on more than one system but is happening in 1.21.
Enabling the DEP OptOut option on the pdfCreator.exe will stop this problem from happening, however this is not an ideal solution.
Note this is a separate issue to a DEP problem previously raised here and fixed in v1.0.0:
http://www.pdfforge.org/forum/help/4800-dep-breaks-pdf-creator-options-menu