Clearing the error "Can't initialize PDFCreator"

Is there an easy way to clear this error once it appears?

Once one of my applications generates this error I can't use PDFCreator again unless I reboot my computer.  (That is, I can't use it again from within any of my MS Access applications, the only way I use it.)

Is there an easier way to clear this than reboooting?

Thanks in advance for any help.  Fred