You are getting the error probably because it is trying to replace the mscomctl.ocx file in \\system32. mscomctl.ocx is a system file and Windows 7 will not let anything fsck around with system32 files unlike Windows XP.
The reason why PDFCreator probably needs *its* version of mscomctl.ocx is because there is some function(s) that it needs that is/are missing from the more recent version in Windows 7. The workaround is to copy the mscomctl.ocx in the same folder as the exe (PDFCreator.exe (?) ) needing it. I'm not sure if it needs to be registered or not as well. If so, the makers of PDFCreator will have to hope that their new MSI packaging tool includes an "Application Isolation" feature to get around that.