Unable to save the settings

We use PDFCreator 1.7.2 on a Windows Server 2012 R2.

After installation of PDFCreator, we can make every settings and after all, we can save the settings. All looks fine and we can print PDF's.

But a few hours (?) later, we can't print PDF's and when we change a setting, we can't save them.

What's the problem in this case?

Thank you for your help.


where/how did you adjust the settings?
Did you install in server mode?