Running Slow

I installed pdfcreator and now certain programs are running slow. ie it can take 30-40 seconds for an app to load and a similat amount of time to load a report within the app. I have unloaded pdfcreator, checked the reg and directories are clear, hard rebooted and I still have the problem.

Everthing was fine before installing pdfcreator. Can anyone shed any light please?